Refractory cytopenia with multilineage dysplasia and eosinophilia
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چکیده
منابع مشابه
Membranous glomerulonephritis in a patient with myelodysplastic syndrome-refractory cytopenia with multilineage dysplasia
A 74-year-old woman presented with edema in the lower extremities. Laboratory tests revealed anemia, thrombocytopenia, hypoalbuminemia, hypercholesterolemia, and nephrotic-range proteinuria. Myelodysplastic syndrome-refractory cytopenia with multilineage dysplasia (MDS-RCMD) was confirmed by bone marrow biopsy. Renal biopsy demonstrated membranous glomerulonephritis (MGN), stage I. Based on the...
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The functional mechanisms involved in angiogenesis and the potential role of endoglin (ENG), recently described as a new marker for this process, have not been explored in Myelodysplastic Syndromes (MDS). In order to gain insight in MDS angiogenesis a combined analysis in bone marrow (BM) of gene expression levels, angiogenesis-related soluble factors and functional angiogenesis-related studies...
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BACKGROUND Myelodysplastic syndrome (MDS) is a preleukemic condition that transforms into acute myeloid leukemia. However, the genetic events underlying this transformation remain poorly understood. Aberrant DNA methylation may play a causative role in the disease and its prognosis. Thus, we compared the DNA methylation profiles in refractory anemia with excess blast (RAEB) to those in refracto...
متن کاملMyelodysplastic syndromes: prognostic significance of multilineage dysplasia in patients with refractory anemia or refractory anemia with ringed sideroblasts.
although full irreversible aggregation was impaired.1 But inhibition of full, irreversible aggregation by wortmannin did not impair thromboxane A2 accumulation in response to LIBS6 plus fibrinogen. These data suggest that the close platelet-to-platelet contact that is brought about by platelet aggregation (primary or full) is not sufficient to generate thromboxane A2 and depends on signaling fr...
متن کاملMyelodysplastic syndromes: prognostic significance of multilineage dysplasia in patients with refractory anemia or refractory anemia with ringed sideroblasts
although full irreversible aggregation was impaired.1 But inhibition of full, irreversible aggregation by wortmannin did not impair thromboxane A2 accumulation in response to LIBS6 plus fibrinogen. These data suggest that the close platelet-to-platelet contact that is brought about by platelet aggregation (primary or full) is not sufficient to generate thromboxane A2 and depends on signaling fr...
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ژورنال
عنوان ژورنال: American Journal of Hematology
سال: 2007
ISSN: 0361-8609,1096-8652
DOI: 10.1002/ajh.20897